Palace's new forward Jean-Philippe Mateta (£5.8m) made his mark against a Brighton defence who had conceded only once in their previous six matches.
In only his second start since arriving in the January transfer window, the 23-year-old netted the opener to claim eight points at the Amex Stadium.
That underlines the form that helped him score 10 goals in 13 starts in the league and cup for German side Mainz 05 this season.
Palace highlights v Brighton
At the back, the return of Tyrick Mitchell (£3.9m) has revived his appeal as the cheapest starting defender in Fantasy.
He had started just one of the previous four matches, with manager Roy Hodgson picking Patrick van Aanholt (£5.4m) at left-back in those contests.
At such low costs, Mateta and Mitchell could appeal to managers looking to play their Wildcard or Bench Boost chips to take advantage of Double Gameweek 26.
Hodgson’s men also have a favourable fixture in Gameweek 28, at home against West Bromwich Albion.
Also in this series
Part 1: GW25 FPL stats: Top captain Bamford provides some relief
Part 2: GW25 Bonus points: Top marks to Dallas
Part 3: FPL Saturday review: Fulham in form for good run
Part 4: FPL Sunday review: Managers rushing to Barnes for Double
Part 6: FPL Tuesday review: Leeds trio reward backers