Both are owned by just 3.5 per cent of managers ahead of Saturday’s 11:00 GMT deadline.
They underlined their explosive potential with double-figure returns in Tuesday's 4-1 home win over Wolverhampton Wanderers.
Jesus scored twice to collect the maximum three bonus points, bringing in his season-high haul of 13 points.
But it was Mahrez who was the star performer over Man City’s two Gameweek 26 matches.
A goal and assist against Wolves followed his assist against West Ham United at the weekend, leaving him with a 17-point return in Double Gameweek 26.
Mahrez has now started Man City’s last four Premier League matches, producing attacking returns in each outing.
Popular pair John Stones (£5.2m) and Ilkay Gundogan (£6.2m) were named among the substitutes on Tuesday.
This came on the back of benchings for Joao Cancelo (£6.2m) and Raheem Sterling (£11.6m) against West Ham.
In fact, a mere four outfield players started both of Man City’s matches in Gameweek 26 – Ruben Dias (£6.1m), Kyle Walker (£6.1m), Kevin De Bruyne (£11.8m) and Mahrez.
Part 1: GW26 FPL stats: Fernandes owners frustrated by Double blank
Part 2: GW26 Bonus points: Mount counts more gains
Part 3: FPL Saturday review: Double delight for City centre-backs
Part 4: FPL Sunday review: Bale back to his best?
Part 5: Who are the best replacements for Barnes in FPL?
Part 6: FPL Monday review: Richarlison extends goal run
Part 8: FPL Wednesday review: Fernandes foiled by Palace defence