The eight teams either were winners of the six groups or one of the two best runners-up.
Tottenham Hotspur v Liverpool
Sunderland v Chelsea
Arsenal v Norwich City
Everton v Fulham
The Under-16 Premier League Cup quarter-final draw has also been made.
The group stage fixtures and the format of the competition mirrored those of the U18 PL Cup.
Chelsea v Norwich City
Everton v Arsenal
West Brom/Middlesbrough v Man City
Liverpool v Leicester City
The quarter-finals of both competitions are one-off matches decided by extra-time and penalties if necessary.
They are scheduled for Saturday, 27 January 2018, but fixture dates are subject to change.