Playing the Triple Captain chip allows you to gain three times a player's points. And as their top-scoring players in FPL, Mane and Salah will be favoured by many managers.
Both have averaged 7.0 points per match this term and are capable of huge hauls. They have six and five double-figure returns respectively.
They have each produced 67 points on the road, compared with the 58 of Mane and the 41 of Salah.
Alexander-Arnold has helped Liverpool record seven successive clean sheets.
Firmino, meanwhile, has been the club's top scorer away from home, scoring all seven of his goals on the road.
Managers seeking alternatives may consider West Ham, the other side who will play twice.
The Hammers travel to Leicester City before their home match with the Reds.
The Frenchman's nine shots in the box since that point have been bettered by just six other players in FPL.
Leicester's Vardy is FPL's top-scoring forward thanks to six double-figure hauls in his 21 Gameweek appearances.
Chuck Booth (@ChuckBoothSport): It's Triple Captain time and, with the gap between games, I believe that both Salah and Mane will play all 180 minutes in Liverpool's fixtures. I'm going with Salah for my Triple Captain solely due to penalties and him lining up as a forward. Every little helps in chasing a Triple-Captain haul to turn around the season. The only other enticing option for me is Alexander-Arnold, with clean sheets becoming automatic for the Reds.
Holly Shand (@FFCommunity_): I'm in an enviable position, with Salah, Mane and Alexander-Arnold in my side. I'm putting my faith in the attacking players and Mane is likely to get the nod given his superior record away from home.
Sam Bonfield (@FPLFamily): It's time to be brave. I'm trusting Firmino with the precious Triple Captain chip!
Lee Bonfield (@FPLFamily): I honestly don't think there's a right or wrong answer for the captaincy this week, as long as you pick one of the Liverpool boys of course! I could make a case for any one of them with Salah's recent underlying stats, Firmino's away goal threat, and seven clean sheets for the defenders. I'll be going for Mane, though, an all-rounder and arguably the best player in the league so far this season. And I'll be Triple Captaining!
Mark McGettigan (@FPLGeneral): Don't overthink the captaincy this week. Go with your gut instinct. I own both Salah and Mane. It's Triple Captain Mane for me.
Ben McNair (@drbenmcnair): I'm no authority on playing the Triple Captain chip, having butchered it for the past few seasons, but I'll be handing it to Salah. I can't see there being a better player with a lower threat of rotation in a Double Gameweek this season.
Paul Gee (@FPLPaulGee): At first I was thinking Mane. However, due to Liverpool's growing number of clean sheets, I'm really tempted by Alexander-Arnold, especially given his attacking abilities.
Part 1: GW24 Ones to watch: Away form enhances Firmino appeal
Part 2: GW24 Differentials: Double lifts value of Snodgrass
Part 4: Scout Selection: Alexander-Arnold among Reds triple-up
Part 5: GW24 Final call: Calvert-Lewin can free funds for Reds duo