The Magpies are the only side scheduled to play twice in each of those Gameweeks, with Joe Willock (£5.7m) and Fabian Schar (£4.3m) their standout recent performers.
Midfielder Willock has produced all of his attacking returns this term in the Magpies’ last three matches, with two goals and an assist.
Centre-back Schar has two double-figure hauls in 11 outings under Eddie Howe, including his season-high 12 points at Brentford last weekend.
Newcastle are among seven sides scheduled to play twice in Double Gameweek 28.
|AVL||SOU (H), LEE (A)|
|CHE||BUR (A), NOR (A)|
|LEE||LEI (A), AVL (H)|
|NEW||BHA (H), SOU (A)|
|SOU||AVL (A), NEW (H)|
|WOL||CRY (H), WAT (H)|
|WAT||ARS (H), WOL (A)|
In goal, their No 1 Martin Dubravka (£4.4m) is a strong budget pick, while Wolverhampton Wanderers' Jose Sa (£5.3m) is also another among the standout DGW28 picks.
Meanwhile, Romain Saiss (£5.0m) and Jan Bednarek (£4.4m) have a strong set-piece threat in defence.
Southampton's schedule after DGW28 makes Armando Broja (£5.5m), James Ward-Prowse (£6.5m) and Che Adams (£6.9m) excellent propositions.
Indeed, according to the Fixture Difficulty Ratings (FDR), four of Saints’ five matches over the next four Gameweeks score only two.
Aston Villa midfielders Philippe Coutinho (£7.4m) and Jacob Ramsey (£4.8m) also have a favourable run of opponents.
In such a scenario, Chelsea would face Burnley and the Canaries, who would entertain Brentford beforehand.
It would also mean both Chelsea and Norwich then have a Blank Gameweek 30.
Managers should therefore wait until the outcome of those midweek FA Cup matches before firming up their plans.
|ARS||LEI (H), LIV (H)|
|BHA||LIV (H), TOT (H)|
|EVE||WOL (H), NEW (H)|
|LIV||BHA (A), ARS (A)|
|NEW||CHE (A), EVE (A)|
|TOT||MUN (A), BHA (A)|
The Toffees' winger Anthony Gordon (£4.5m) boasts strong home form and has impressed under Frank Lampard, while Gunners' trio Bukayo Saka (£6.5m), Gabriel Martinelli (£5.3m) and Gabriel (£5.3m) are also favourably-priced.
Managers who still have their Triple Captain chip could be tempted by another two matches for Liverpool's Mohamed Salah (£13.1m). His team-mate Sadio Mane (£11.7m) is owned by just 3.2 per cent and has proven a key differential recently.
Harry Kane (£12.2m) and Son Heung-min (£10.8m) look back to their best and are finally justifying their premium price tags in Fantasy ahead of another DGW for Tottenham Hotspur.