The Portuguese starred on his second debut for Manchester United, netting either side of half-time to claim 13 points plus three bonus.
GW4 most transferred-in players
|Player||Transferred in by ('000s)||Pts|
Out-of-position midfielder Ferran Torres (£7.1m) gained 1.2m new owners after starting the season as a centre-forward for Manchester City.
But the Spaniard was unable to justify that backing as he blanked in the 1-0 win at Leicester City.
There was also misery for the 990,000+ who added Michail Antonio (£8.0m) to their squads.
Salah still top captain
Mohamed Salah (£12.5m) was once again the most-popular captain, backed by over 1.7m managers. It's the third time the Egyptian has been the No 1 pick in 2021/22.
Bruno Fernandes (£12.0m) was chosen just ahead of Ronaldo in second spot with over 1.3m handing him the armband.
Fernandes had scored and assisted in both his previous appearances against Newcastle and was once more on target against the Magpies.
The Portuguese also received a bonus point for his efforts to return eight points.
GW4 most-captained players
|Player||Captained by (000's)||Pts|
Ronaldo was the top captain pick among the leading 100 Fantasy managers and those managers among the elite will be smiling after his double-digit haul.
Salah took second spot and Romelu Lukaku (£11.5m) joined Fernandes in third.
Most-captained by top 100
Fernandes and Danny Ings (£8.0m) were the makeweights as managers reshaped their squads to accommodate Ronaldo.
And Emiliano Martinez (£5.5m) was shipped out by over 970,000 to complete the top three. The Villa goalkeeper missed the trip to Stamford Bridge due to quarantine regulations.
GW4 most transferred-out players
|Player||Transferred out by ('000s)||Pts|