Harry Kane heads into the final day with the slimmest of advantages as he looks to claim the Premier League Playmaker of the Season award for the first time.
The England international will need to improve on his recent record, having failed to produce an assist in his last nine appearances.
He does, however, face a Leicester side who conceded four times in their previous home match when they lost 4-2 to Newcastle United.
Kane, who is tied with Liverpool's Mohamed Salah in the race for the Golden Boot on 22 goals, is aiming to become only the third player to finish a season as both top scorer and the player with the most assists.
Fernandes registered an assist in a 1-0 victory over Wolves in the reverse fixture and a repeat performance at Molineux could lead to the Portuguese star earning a share of the prize.
Wolves have failed to keep a clean sheet in their last five encounters ahead of Nuno Espirito Santo's final match in charge.
City midfielder De Bruyne could return on Sunday after recovering from injury, although he faces a difficult task against an Everton defence who have kept four consecutive clean sheets away from home.
The Belgian is looking the win the award for the third time, after receiving the honour in 2017/18 and 2019/20.