The Scout reviews every Fantasy Premier League fixture, whether it's noting player rotation or injuries, tactical observations or highlighting in-form differentials.
The Frenchman supplied the assist for Marcus Rashford’s (£9.0m) goal before scoring the second, earning a 13-point return.
Martial has now found the net in each of his last five outings at Old Trafford, totalling 64 points.
Meanwhile, Bruno Fernandes (£9.0m) had to settle for just an assist against the Saints.
The Portuguese was the second-top captain pick for Gameweek 35+, having produced three successive double-digit returns.
However, it was a disappointing evening for Mason Greenwood (£4.9m), the most-bought player in the Gameweek.
The teenage striker earned over 433,000 transfers in but recorded his first blank in four matches.
In defence, Man United have worries at left-back for their visit to Crystal Palace. Luke Shaw (£5.4m) was forced off with a knock, while his replacement, Brandon Williams (£3.9m), sustained a head injury.
For Southampton, Stuart Armstrong’s (£5.2m) opener took his tally to three goals and two assists in his last five starts.
And the remaining schedule suggests he can continue to offer excellent value.
Top scorer: Anthony Martial 13pts (TSB 20.2% £8.3m)
Bonus points: Anthony Martial 3pts, Jan Bednarek 2pts, Marcus Rashford 1pt, Stuart Armstrong 1pt.
Man Utd: CRY (A) WHU (H) LEI (A)
Southampton: BHA (H) BOU (A) SHU (H)