The forward has a goal or an assist in each of his last 10 Gameweek starts, making him the top captain pick in the last two Gameweeks.
Pogba has been transformed as an FPL option since Ole Gunnar Solskjaer was appointed caretaker manager.
The midfielder boasts four goals and four assists from four Gameweek appearances with the Norwegian in charge.
He has recorded 49 of his 100 points for the season in those matches, serving up three double-figure hauls.
But there are in-form alternatives on both sides in Sunday's encounter at Wembley.
The United forward is the most-bought player in the Gameweek, with more than 174,00 new owners after three goals and two assists in his four starts under Solskjaer.
Pierre-Emerick Aubameyang (£11.4m) is another striker who can have a major say on the armband decision.
Aubameyang has four goals, an assist and 31 points in the last four Gameweeks.