News of the striker's potential omission from the Gameweek 21 visit to Leicester City sparked almost 300,000 FPL managers to move Costa out of their squads; a trend that has continued ahead of this weekend.
The striker has been sold by another 267,000 prior to Sunday's visit of Hull.
Antonio Conte will consider the Spaniard for a starting role against the Tigers, who arrive at Stamford Bridge having shipped 24 goals in 10 away trips and with fitness doubts over Robert Snodgrass (£5.8m).
Found in 11.8% of FPL squads, Snodgrass has scored or assisted 50% of Hull City's goals this season, returning attacking points in his last three Gameweeks.
Philippe Coutinho (£8.3m) is another major FPL asset set for a return in Gameweek 22.
Having started and played 65 minutes in Liverpool's midweek FA Cup replay against Plymouth Argyle, the Brazilian is poised to face Swansea City at Anfield.
Prior to his injury in Gameweek 13, Coutinho supplied a goal or assist in three of his previous four home matches.
A meeting with the Swans offers a platform for an immediate return to FPL prominence given that Paul Clement's side have conceded three or more goals in seven of their last nine matches.
Elsewhere in Jurgen Klopp's squad, both Nathaniel Clyne (£5.8m) and Jordan Henderson (£6.3m) are pushing to shake off injuries, while Joel Matip (£5.3m) is available again following international clearance from FIFA.
The Frenchman returned to training this week following an ankle problem sustained at Swansea City in Gameweek 21.
Giroud has supplied goals in each of his last four Premier League outings and his availability may Alexis Sanchez (£11.9m) in a left-flank role.
Nonetheless, the Chilean amassed 17 goal attempts over his previous two home matches from that position.
Owned by 9.1% of FPL managers, the Belgian could be replaced in Mauricio Pochettino's line-up by either Ben Davies (£4.7m) or Kevin Wimmer (£4.6m), opening up a cheaper route into the Spurs defence for FPL managers.
For Manchester City, head coach Pep Guardiola is considering a first squad call-up for new signing Gabriel Jesus (£9.0m).
Recently deployed at wing-back and with three clean sheets, a goal and an assist in his last four Gameweeks, Baines has proved a popular recent target.
Acquired by more than 110,000 FPL managers prior to Gameweek 21, he has picked up a further 56,000 suitors ahead of this weekend.
However, Baines' rib injury will need assessment prior to the encounter with Crystal Palace.