Nwaneri came on in stoppage time of Arsenal's 3-0 win at Brentford that took them back to the top of the table.
He also became the youngest player to appear in top-flight history. Derek Forster was the previous record-holder having played for Sunderland in 1964 aged 15 years and 184 days.
|Ethan Nwaneri||ARS||BRE 0-3 ARS||15y 181d|
|Harvey Elliott||FUL||WOL 1-0 FUL||16y 30d|
|Matthew Briggs||FUL||MID 3-1 FUL||16y 68d|
|Isaiah Brown||WBA||WBA 2-3 WIG||16y 117d|
|Aaron Lennon||LEE||TOT 2-1 LEE||16y 129d|
"It was a pure gut feeling," Arsenal manager Mikel Arteta told the club's official website. "I met the boy, I really liked what I saw. Per [Mertesacker] and the academy staff gave me really good information about him.
"It’s another step, another experience. I think it sends a really strong message about who we are as a club."
"Oh my word... to bring him on he must be showing something," he said.