The fixture has been ruled off due to an outbreak of COVID-19 in the Spurs camp.
Son Heung-min (£10.4m) and Sergio Reguilon (£5.3m) are by far the most popular players in the Spurs squad, selected by 19.0 per cent and 16.2 per cent respectively, while 18.7 per cent of managers own Brighton goalkeeper Robert Sanchez (£4.6m).
The Scout looks at the best options across the price brackets for those seeking Son and Reguilon replacements for Gameweek 16, as well as alternative 'keepers to Sanchez.
Jarrod Bowen (WHU) £6.5m
The West Ham United winger has blanked in just three of his last 10 starts, returning 62 points from Gameweek 5 onwards. Bowen’s 31 shots in that time rank third among all players in Fantasy.
Bernardo Silva (MCI) £7.6m
Back-to-back double-figure hauls have made the Manchester City midfielder the top target for managers in Gameweek 16. Silva has earned a massive 589,000+ transfers in for his home encounter with Wolverhampton Wanderers.
Diogo Jota (LIV) £8.0m
A role up front has lifted the output of Liverpool’s Portuguese star. Jota has scored four goals and returned 33 points over the last four Gameweeks, just two points fewer than Mohamed Salah (£13.1m) during that period.
Marcus Rashford (MUN) £9.4m
Listed as a midfielder in Fantasy, he was handed a role up front in Ralf Rangnick’s first match in charge of Manchester United against Crystal Palace. Four of their next five contests score only two in the Fixture Difficulty Ratings (FDR).
Diogo Dalot (MUN) £4.4m
He was selected ahead of Aaron Wan-Bissaka (£5.1m) at right-back by Rangnick last weekend. Dalot helped Man Utd to their first home clean sheet of 2021/22, earning eight points.
Vladimir Coufal (WHU) £4.7m
Injuries to fellow full-backs Aaron Cresswell (£5.4m) and Ben Johnson (£4.0m) can help the Czech reclaim a starting role for West Ham. Four of the Hammers' next five matches score only two in the FDR.
Marcos Alonso (CHE) £5.7m
An injury to rival Ben Chilwell (£5.7m) has allowed the Spaniard a return to the Chelsea starting XI. Owned by just 10.1 per cent, Alonso is an explosive differential with big potential at both ends of the pitch.
Meanwhile, the postponement also poses problems for a number of owners of Brighton’s No 1 Robert Sanchez.
The Spaniard is the third most-popular goalkeeper in Fantasy, selected by 19.1 per cent.
More than 388,000 of those managers also own Watford’s Ben Foster (£4.1m), who is injured. That means they are currently without a goalkeeper this weekend.
Similarly, a further 109,325 own Sanchez and Brighton’s back-up Jason Steele (£4.0m).
Arsenal’s Aaron Ramsdale (£5.0m) is the standout replacement, his average of 4.9 points per match (ppm) better than any other regular starting goalkeeper this season.
Man Utd’s David De Gea and West Ham’s Lukasz Fabianski (both £5.0m) are low-owned alternatives with strong schedules ahead.
Both Spurs and Brighton now have two outstanding matches yet to be rescheduled, which will lead to Double Gameweeks later in the season.