The Arsenal forward has suffered a poor run of returns, blanking in four successive fixtures.
But his record against opponents in the bottom six suggests he can get back on the scoresheet.
Aubameyang's nine goals in such matches is joint top with Jamie Vardy (£9.8m) among all players this season.
He is handed the armband in a 3-4-3 formation, with Anthony Martial (£8.1m) named vice-captain.
Manchester United's playmaker has been a consistent source of returns on his travels. Fernandes visits Brighton & Hove Albion on the back of 25 points in his three away matches since arriving at Old Trafford in January.
The most-bought player in the Gameweek, the Frenchman has earned over 192,000 new owners after his hat-trick against Sheffield United. Martial has six goals in his last six appearances.
The Tottenham Hotspur winger can thrive against a Sheff Utd side who have lost 3-0 in each of their last two matches. Son has been Spurs' most productive player under Jose Mourinho, averaging 6.1 ppm.
The 31-year-old scored twice to earn a 13-point haul in his previous meeting with Norwich.
More than 150,000 managers have turned to the Man Utd forward for the encounter with Brighton. Rashford's 24 big chances and 35 shots on target are both team-leading totals this term.
The Mexican heads to Villa Park having scored in three of his last four Gameweek appearances. Away from home, Jimenez's 49 shots and 22 shots both rank among the top two players in 2019/20 FPL.
Tom (@WGTA_FPL): As it stands, I'm joining the Selection team with Aubameyang as captain, a last roll of the dice for Arsenal's talisman. Wish us luck. We'll need it!
Ash (@FPLHints): Having failed to score in four consecutive matches, Aubameyang may not be the best captain pick. But, then again, he's up against a Norwich team riddled with injuries and poor form. Sarr will also need to prove his worth in a must-win encounter for Watford.
Chuck Booth (@ChuckBoothSport): Son was already unlucky to not score v West Ham and Spurs seem to be finding their feet. As the wheels begin to come off for the Blades, there could be goals on offer for Mourinho's men.
Ben McNair (@drbenmcnair): I like the Son pick-up against a Sheff Utd side who have been struggling of late and face a short turnaround after their FA Cup tie this weekend.
Paul Gee (@FPLPaulGee): I love the triple-up on Man Utd as they are on fire, although Brighton are in decent form. Having watched the last Arsenal match, Aubamayang is just playing too deep for my liking and I wouldn't captain him.