The Norwich City midfielder's third strike in six Gameweeks took his total to 71 points this season.
He has now returned 15.1 points per million in FPL, more than any other midfielder.
But many of his 19.9 per cent ownership are set to miss out on his 10-point return.
Cantwell was the fifth most-benched player in the Gameweek, with 571,000+ naming him as a substitute.
Jack Grealish (£6.2m) is another budget-friendly midfielder in strong form.
The Aston Villa midfielder was the third most-bought player in Gameweek 18, earning 270,000 new owners.
And he rewarded their faith with the hosts’ only goal in a 3-1 home defeat by Southampton, his seventh attacking return in his last nine starts.
Danny Ings (£6.4m) scored twice at Villa Park to record a 13-point haul, the highest of Gameweek 18 so far.
The Southampton forward has 10 goals in the last 12 Gameweeks, second only to the 14 of Jamie Vardy (£10.1m) in that period.
Vardy was the most-captained player of Gameweek 18 and he continued his incredible run of form.
The Blades' Dean Henderson (£4.8m) became only the second goalkeeper to provide an assist this season, his long pass leading to the only goal by Oliver McBurnie (£5.7m) in the win over Brighton & Hove Albion.
Henderson is the top-scoring goalkeeper in FPL after his 12-point haul at the Amex Stadium.