From Sunday's win over Fulham giving Liverpool a record start, to Wolverhampton Wanderers going into uncharted territory at Arsenal, see the need-to-know facts from the weekend's matches.
For more statistics on each match, click on the results below.
Cardiff 2-1 Brighton
This became the 100th different fixture to have been played in all four top divisions of English football.
Huddersfield Town 1-1 West Ham
Alex Pritchard is the first Huddersfield Town player to score a PL goal at home in 726 minutes of action, since Tom Ince against Watford in April.
Leicester City 0-0 Burnley
Leicester mustered 22 shots in the match, the most they have attempted in a PL fixture without scoring since they returned to the top flight in 2014/15.
Newcastle United 2-1 Burnley
Newcastle have won their first consecutive Premier League matches since April, when they won four in a row.
Southampton 1-1 Watford
Watford's Jose Holebas, with two goals and four assists, is the defender directly involved in the most Premier League goals this season.
Crystal Palace 0-1 Spurs
Spurs have won 12 Premier League away matches in 2018, the most in the division.
Liverpool 2-0 Fulham
Liverpool's total of 30 points from their opening 12 Premier League matches is their joint-best, level with 2002/03.
Chelsea 0-0 Everton
Chelsea are unbeaten after their opening 12 matches for only the second time, also doing so in 2014/15 when they won the title.
Arsenal 1-1 Wolves
Ivan Cavaleiro's goal gave Wolves their first-ever lead in the Premier League against Arsenal, at the ninth attempt.
Man City 3-1 Man Utd
Ilkay Gundogan's goal came after a 44-pass move, the most for a Premier League goal since the 45 passes before Juan Mata scored for Man Utd v Southampton in September 2015.