Morata is owned by 29.3% of the game and ranks second behind Harry Kane (£12.9m) in the forward standings.
Morata is being shifted out of squads at pace ahead of tonight's 18:45 GMT deadline, with more than 467,000 selling him.
His absence could persuade head coach Antonio Conte to move to a 3-4-2-1 formation at John Smith's Stadium.
Another premium-priced forward is pushing for a return to the Manchester City line-up.
Sergio Aguero (£11.6m) was handed the captaincy by 5.3% of managers for Gameweek 16 after starting three successive PL matches.
Swansea's Tammy Abraham (£5.9m) may have to settle for a place on the bench against the leaders.
He could start if head coach Paul Clement opts for a lone striker system, leaving Abraham to make an impact from the bench.
Sold by 55,000+ managers in the Gameweek, Abraham has produced attacking returns in two of his three substitute appearances.
The Welshman had produced a goal or assist in six of the previous seven Gameweeks prior to Sunday's draw at Southampton.
But after sustaining a hamstring problem at St Mary's Stadium, Ramsey is the most transferred-out midfielder in the Gameweek with 41,000+ sales.
They were drafted in by 298,000 and 220,000 FPL managers respectively for the Gameweek 16 Merseyside derby but were used only as second-half substitutes.
Manager Jurgen Klopp could revert to his preferred 4-3-3 set-up against the Baggies. This would allow Coutinho to feature in central midfield, with Firmino flanked by Sadio Mane (£9.4m) and Mohamed Salah (£9.9m) in a front three.
The defender had supplied 28 points in the three Gameweeks before getting injured in the 2-2 draw with AFC Bournemouth.
Scott Dann (£4.7m) is set to return to Roy Hodgson's back four having replaced Sakho to score Palace's second goal against the Cherries.