Burnley's Chris Wood returns after sitting out the last match following a long trip back from international duty.
Tom Heaton (shoulder) and Jonathan Walters (knee) remain sidelined, while Dean Marney (knee) is training as he closes in on a first appearance of the season.
Arsenal are without Theo Walcott, who is building up his fitness following illness, and Santi Cazorla (Achilles).
But Danny Welbeck, who only played for the first half on his return from injury against Cologne on Thursday, is available.
Did you know?
Arsenal won both Premier League matches against Burnley last season thanks to 90th-minute goals; only the second occasion of a team doing so home and away against the same opponent in the competition.
Burnley have 22 points from their 12 PL matches his season and are only 18 points off their best ever points tally (40 in 2016/17).
Alexis Sanchez has scored four goals in his five meetings with Burnley in all competitions, though is yet to net at Turf Moor.
Mesut Ozil has created more goalscoring chances from open play this season than any other player (30).
What the managers say
Sean Dyche: "You have to stay focused all the time, that’s the biggest thing, because they can pounce and hurt you at any time."
See: Dyche ready for major challenge
Arsene Wenger: "They have won with 25 or 30% possession. That means they are calm, they know what to do and they are patient, with that killing instinct of a snake."
See: Latest on Welbeck and Walcott
Referee: Lee Mason
Assistants: Harry Lennard, Matthew Wilkes
Fourth official: Jonathan Moss
