Arsenal striker Olivier Giroud is unlikely to be fit and Shkodran Mustafi and Danny Welbeck will be assessed on Friday.
Tottenham Hotspur have Harry Kane, Dele Alli, Harry Winks, Hugo Lloris and Michel Vorm back in full training.
Toby Alderweireld (hamstring) and Victor Wanyama (knee) are still out.
Did you know?
Arsenal are on their longest ever winless run against Tottenham Hotspur in the Premier League, having drawn four and lost two of the last six matches against them.
Arsenal have won their opening five home matches to a PL season for the first time since 2009/10. They last won their first six at home in 2007/08.
Harry Kane has scored in all five of his PL north London derbies, netting six goals in total. Only Emmanuel Adebayor (8) and Robert Pires (7) have scored more goals in this fixture.
Mauricio Pochettino has yet to lose a PL north London derby (W2 D4), though all three of his visits to Emirates Stadium as Spurs manager have been draws.
What the managers say
Arsene Wenger: “It’s always a fierce derby. As well to keeping your nerve, you must have full commitment while being lucid and calm enough to focus on the game."
See: Wenger on Lacazette and Kane plan
Mauricio Pochettino: "It’s a massive game, an important game and it means more than three points. Like always in a derby, you play for your emotions, not only for the three points."
See: Pochettino on derby preparations
Referee: Mike Dean
Assistants: Ian Hussin, Eddie Smart
Fourth official: Kevin Friend
