The Cherries centre-back produced 16 clearances, blocks and interceptions (CBI), four recoveries and a successful tackle to earn his side a third away clean sheet of the season.
Saints defender Jack Stephens (£4.0m) tallied 30 in the BPS to collect two bonus points.
The 23-year-old made five CBI, six recoveries and won two successful tackles, in addition to completing 83% of 78 attempted passes.
Yoshida registered eight CBI and eight recoveries, completing 92% of 78 completed passes.
Boruc made four saves and five recoveries, while Smith produced three successful tackles, five recoveries and two CBI in a solid defensive display.
Drafted in by 123,000+ FPL managers for Gameweek 30, AFC Bournemouth’s Joshua King (£5.8m) disappointed his 13.2% owners by failing to produce a single shot on goal before being replaced on 69 minutes.
King was also unfortunate to miss out on attacking returns having been replaced before Harry Arter’s (£5.0m) late missed penalty. Howe has confirmed that King remains the designated taker when on the pitch.
With Southampton playing 10 times in the final eight Gameweeks, both Stephens and Yoshida offer FPL managers budget options in defence for the run-in.
In attack, the continued absence of Manolo Gabbiadini (£6.8m) has dented their appeal, though.