Manuel Lanzini could be key to West Ham United's chances of beating Premier League leaders Chelsea if he continues his impressive London derby record.
Elsewhere this weekend, Tottenham Hotspur are bidding for a club record winning streak at White Hart Lane and Manchester United have a landmark in their sights when AFC Bournemouth visit Old Trafford.
Saturday 4 March
Manchester United v AFC Bournemouth
Man Utd are aiming to become the first side to win 600 Premier League matches (P949 W599 D203 L147)
Leicester City v Hull City
Hull could be the first promoted side to beat defending champions twice in one PL season
Stoke City v Middlesbrough
Stoke's seven-match unbeaten home run in the PL (W3 D4 L0) is their longest since a 17-match streak in 2012
Swansea City v Burnley
Gylfi Sigurdsson has assisted a league-high five goals from set pieces this season
Watford v Southampton
Manolo Gabbiadini could become the first Saints player to score on his opening three PL matches for the club
West Bromwich Albion v Crystal Palace
West Brom have scored a league-high 12 goals from corners this season
Liverpool v Arsenal
There have been 16 goals scored in the 90th minute or later in this fixture; a Premier League high
Sunday 5 March
Tottenham Hotspur v Everton
Victory would give Spurs a club record ninth successive PL home win
Sunderland v Manchester City
Only against Wigan (10) has Jermain Defoe scored more PL goals than he has versus Man City (8)
Monday 6 March
West Ham United v Chelsea
Manuel Lanzini has scored in seven of his 11 Premier League London derbies
