The 25-year-old limped off in the 80th minute with what appeared to be a groin problem, and is now set for a spell on the sidelines.
A Man Utd statement says: “Marcus Rashford will be unavailable for Thursday’s UEFA Europa League quarter-final game against Sevilla because of a muscle injury.
“Subsequent assessment of the injury suggested that Marcus will be unavailable for a few games, but is expected to be back for the season run-in.”
"He is optimistic and he has started straight on his recovery and his rehab. That helps him to get back soon. It's a few games. I can't give more details because we have to see how the injury develops."
Shaw fitness update
“No, [they are] both not available,” said Ten Hag. “Definitely the injury of Garnacho is more severe, is more strong, but Luke Shaw I expect him back at short notice, yes.”
Busy spell ahead
Having scored 31 goals for club and country this season, Rashford's injury comes at a bad time as Man Utd prepare for eight matches in the space of 25 days.
In addition to their quest for a top-four finish in the Premier League, the Red Devils are in the quarter-finals of the UEFA Europa League (UEL) and the semi-finals of the FA Cup (FAC).
Man Utd fixtures
|Thu 13 Apr||UEL||Sevilla (H)|
|Sun 16 Apr||PL||Nott'm Forest (A)|
|Thu 20 Apr||UEL||Sevilla (A)|
|Sun 23 Apr||FAC||Brighton (N)|
|Thu 27 Apr||PL||Spurs (A)|
|Sun 30 Apr||PL||Aston Villa (H)|
|Thu 4 May||PL||Brighton (A)|
|Sun 7 May||PL||West Ham (A)|
Rashford's injury is bad news too for a host of Fantasy Premier League managers, given he is in 50.8 per cent of squads.
He was the second most-captained player last weekend, in Gameweek 30, handed the armband by more than 1.2 million FPL bosses.
Even before today's news, Rashford was already the most-sold player since suffering his injury, with more than 335,000 Fantasy managers letting him go this week. Sales will only accelerate now after the confirmation that he will miss matches.