Arsenal moved eight points clear at the top of the table following a pulsating 0-0 draw with third-placed Newcastle United.
It was a frustrating night for Arsenal, who dropped points at home for the first time this season as they could not find a way through a well-drilled Newcastle defence.
Joelinton headed wide for the visitors in first-half stoppage time while Arsenal's best opportunity came in the dying moments but Nick Pope produced a stunning save with his legs to deny Eddie Nketiah.
The draw takes Arsenal to 44 points while Newcastle remain third, nine points behind, having played a match more.
Goals from Casemiro, Luke Shaw and Marcus Rashford maintained Manchester United's fine form as they recorded a 3-0 win against AFC Bournemouth.
Christian Eriksen whipped over a free-kick that Casemiro volleyed in on 23 minutes.
Shaw doubled the advantage just after the break with his first Premier League goal since March 2021 before Rashford added a third with his seventh goal of the season.
Man Utd are fourth, level on 35 points with Newcastle. AFC Bournemouth stay 15th with 16 points.
Aleksandar Mitrovic equalled his best-ever return in a Premier League season as his 11th goal of the campaign secured a 1-0 win for Fulham at Leicester City.
Willian was the provider with a superb 17th-minute delivery and Mitrovic did the rest, taking a touch before slamming the ball home.
Youri Tielemans rattled the bar late on but Leicester could not find a way through.
A third consecutive win takes seventh-placed Fulham to 28 points. Leicester stay 13th with 17 points.
Three goals in six second-half minutes sealed a 4-1 win for Brighton & Hove Albion at Everton.
Brighton opened the scoring on 14 minutes through Kaoru Mitoma before Evan Ferguson, on his full Premier League debut, side-footed home a second after 51 minutes.
Further efforts by Solly March and Pascal Gross in the 54th and 57th minutes, made the score 4-0 before Demarai Gray scored a consolation from the penalty spot in stoppage time.
Everton's seventh defeat in 10 matches leaves them two places and one point above the bottom three, having played one match more than their relegation rivals.
There are four matches on Wednesday when Tottenham Hotspur will look to bolster their top-four challenge with a first win in three outings at Crystal Palace.
The remaining three fixtures feature the bottom four teams.
Any one of the three sides currently in the drop zone - Southampton, Wolverhampton Wanderers and Nottingham Forest - could move out of the bottom three with a win.
At St Mary's Stadium, Southampton will be hoping to move off the foot of the table with a win against third-bottom Forest.
Wolves make the short trip to in-form Aston Villa, while West Ham United visit Leeds United aiming to end a run of five consecutive defeats that has left the Hammers only one place and point above the drop zone.