Manchester City moved a huge step closer to back-to-back Premier League titles with a 5-1 victory over Wolverhampton Wanderers on Wednesday, a result that takes them three points clear of Liverpool with two matches left.
With just two matches remaining and City only needing four more points to guarantee top spot, they can move to the brink this weekend.
City edged past the Hammers 2-1 when the teams met in the reverse fixture, and another triumph would leave them with one hand on the trophy.
The main concern for the leaders is they lost yet another defender to injury on Wednesday. With Fernandinho already filling in at the back against Wolves, Aymeric Laporte limped off with a knee problem, joining Ruben Dias, John Stones and Kyle Walker in the treatment room.
Liverpool resume their Premier League programme at Southampton on Tuesday, 17 May, in a match they may have to win to prevent City being crowned champions that night.
And even if Spurs win the duel, Chelsea can finish the job themselves with a home win over Leicester City next Thursday, 19 May.
Everton moved two points clear of danger with a 0-0 draw at relegated Watford.
Leeds will seek to overtake a Burnley side who have a tough trip to Tottenham Hotspur.