The Crystal Palace winger has a reliable recent record against the Seagulls, scoring four goals in their last four meetings at Selhurst Park.
Zaha was also in fine form in his previous home appearance in Gameweek 4, earning 12 points in a 3-0 win over Tottenham Hotspur thanks to a goal and assist.
That earns him a place in a Scout Selection that lines up in a 3-5-2 formation, with Cristiano Ronaldo (£12.7m) handed the armband and Mohamed Salah (£12.6m) named vice-captain.
The Crystal Palace No 1 has been a consistent source of returns at home this season. Guaita has kept a clean sheet in both his matches at Selhurst Park, totalling 15 points.
Liverpool’s Egyptian has averaged 10ppm this term, claiming double-figures in three of his five appearances. Salah is the most-owned player in Fantasy, found in over 57 per cent of squads, and is expected to be the top captain pick against Brentford.
An ownership of 5.5 per cent highlights his appeal as a differential for Monday’s encounter with Brighton.
The Leicester wide man has delivered double-figure hauls in each of his last two home matches with Burnley. Barnes also produced a goal and an assist in the UEFA Europa League against Napoli at King Power Stadium last week.
The Portuguese has been very unfortunate to record successive blanks. Playing as a centre-forward, Jota has produced seven shots and created seven chances in the last two Gameweeks.
Ronaldo has four goals in three matches in all competitions after returning to Old Trafford. Since making his second debut for the club in Gameweek 4, the Man Utd star's 13 shots and 12 shots in the box are both more than any other player in Fantasy.
West Ham United’s forward has produced double-figures in three of his four appearances this term. Facing a Leeds United defence who are without a clean sheet in 2021/22, Antonio is among the top captain options for Gameweek 6.
Remember, the Gameweek 6 deadline is at 11:00 BST on Saturday 25 September.