According to the Fixture Difficulty Ratings (FDR), both of those matches score only two.
Crucially, David Moyes' men are still involved in the competition for European places, which suggests they are unlikely to rotate.
The recent return of forward Michail Antonio (£6.5m) from injury offers managers a big differential.
Owned by only 6.8 per cent, he netted twice in his comeback appearance against Burnley in Gameweek 34, earning his season-high haul of 13 points.
Jesse Lingard (£6.6m) has frustrated his 29.8 per cent backers with a run of three successive blanks.
Nonetheless, he remains West Ham’s most explosive player in Fantasy this term.
Lingard has produced five double-figure hauls in his 13 outings, more than any team-mate.
Moyes’ side conceded just one goal in their matches with their two upcoming opponents earlier this season, boosting the appeal of their key defenders.
Aaron Cresswell (£5.6m) offers the strongest all-round potential at the back, combining 10 assists with 10 clean sheets.
However, Vladimir Coufal (£4.8m) could prove a value option if the left-back fails to recover from a leg problem.
The Czech has supplied four of his eight assists this season over the last six Gameweeks.