Leicester City's James Maddison (hip), Ayoze Perez (knee), Wesley Fofana (hamstring), Denis Praet (hamstring) and Wes Morgan (back) are ruled out.
Arsenal report no fresh injury concerns.
Leicester have won four of their last six Premier League matches against Arsenal (D1 L1), one more than in their previous 36 top-flight league contests with them (D10 L23).
Only Wayne Rooney (12) has scored more PL goals against Arsenal than Leicester's Jamie Vardy, who has netted 11 times in 12 appearances against them.
Arsenal have lost their last three PL matches at Leicester, receiving more red cards (2) than goals scored (1) in these three contests.
Pierre-Emerick Aubameyang has scored 38 goals in 50 PL matches played on a Sunday, 14 more than he has on all other days of the week combined in the competition (24 in 56).
Referee: Paul Tierney. Assistants: Dan Cook, Harry Lennard. Fourth official: Michael Oliver. VAR: David Coote. Assistant VAR: Nick Hopton.