West Ham United are targeting an opening-day victory for the first time since a 2-0 win at Arsenal in 2015/16.
Newcastle United will aim for a repeat of last season's result when they won 3-2 at London Stadium.
Team news
Tomas Soucek returned from international duty and has been back in training with West Ham ahead of Saturday's opening match.
Jamaal Lascelles is available for Newcastle after serving a one-match ban in the friendly at Stoke City. Matt Ritchie and Ciaran Clark (both knocks) missed that match but have recovered while Jonjo Shelvey returned to training this week.
Dwight Gayle is a long-term absentee following surgery on a knee injury.
Did you know?
West Ham have scored two or more goals in each of their last five league matches against Newcastle.
Michail Antonio ended last season with eight goals in his last seven Premier League appearances for the Hammers. In terms of monthly hauls that July tally of eight has been bettered only by Luis Suarez's 10 goals for Liverpool in December 2013.
Jonjo Shelvey has scored three Premier League goals against West Ham, his joint-best against one club.
Newcastle have won nine PL matches at West Ham, only at Tottenham Hotspur do they have a better away record with 10 wins.
Match officials
Referee: Stuart Attwell. Assistants: Constantine Hatzidakis, Neil Davies. Fourth official: Darren England. VAR: Peter Bankes. Assistant VAR: Simon Long.
