Manchester City are aiming to build a winning run and overtake second-placed Leicester City.
Everton are seeking to extend a five-match unbeaten run and strengthen their position in the top half.
Team news
Goalkeeper Ederson returns for Man City after completing a one-match suspension, while striker Gabriel Jesus (illness) is also in contention.
David Silva (knock) and John Stones (hamstring) both face fitness tests, but Aymeric Laporte and Leroy Sane (both knee) remain sidelined.
Everton's Morgan Schneiderlin (calf) is set to return to full training on Tuesday, but the match comes just too soon.
Alex Iwobi (hamstring) continues his rehabilitation while Jean-Philippe Gbamin (thigh) and Andre Gomes (ankle) remain long-term absentees.
Did you know?
Man City’s Gabriel Jesus has scored in his last four Premier League matches against Everton. His total of five goals against the Toffees is the most he has scored against any top-flight side.
If Man City beat Everton it will be the first time they have won five Premier League matches in a row against the Toffees.
Everton are looking to win consecutive Premier League away matches for the first time since September 2016.
Dominic Calvert-Lewin scored five Premier League goals in December 2019, the most by a Toffees player in a single month since Romelu Lukaku also scored five in February 2017.
Match officials
Referee: Andre Marriner. Assistants: Scott Ledger, Simon Long. Fourth official: Kevin Friend. VAR: David Coote. Assistant VAR: Andy Halliday.