Liverpool go into the Merseyside derby aiming for a sixth successive victory as they seek to maintain or increase their eight-point lead at the top.
Everton are bidding to respond after back-to-back defeats to Norwich City and Leicester City, which have left them one place and two points above the bottom three.
Team news
Joel Matip (knee) remains unavailable for Liverpool, while goalkeeper Alisson is suspended after his red card against Brighton & Hove Albion on Saturday.
Everton's Theo Walcott has recovered from illness and is available, but Seamus Coleman (rib) and Fabian Delph (hamstring) remain major doubts.
Jean-Philippe Gbamin (thigh) and Andre Gomes (ankle) are long-term absentees.
Did you know?
Liverpool are unbeaten in their last 17 Premier League matches against Everton (W7 D10), their longest ever undefeated run against one opponent in the competition.
The Reds have scored more winning goals in the 90th minute or later against Everton in the Premier League than any side has against another in the competition’s history, with five. Divock Origi netted one in this fixture last season.
Everton have conceded more 90th-minute Premier League goals than any other side this season, with four, and have suffered such a blow in their last two matches against Norwich City and Leicester City.
Jurgen Klopp can become the second-fastest manager to reach 100 Premier League wins, in his 159th match. Jose Mourinho reached that mark in 142 matches. Klopp would also be the fastest Liverpool manager to 100 top-flight wins.
Match officials
Referee: Mike Dean. Assistants: Darren Cann, Dan Robathan. Fourth official: Anthony Taylor. VAR: Martin Atkinson. Assistant VAR: Andy Halliday.
