The Premier League's bottom two teams meet at Carrow Road in the first fixture of Matchweek 12.
Norwich City can move up one place with victory, a point from safety, while a win for Watford would lift them above their hosts.
Team news
Mario Vrancic could be in contention for Norwich City confirms Daniel Farke, who has no new injury concerns ahead of Friday night's clash.
Todd Cantwell and Ibrahim Amadou have recovered from respective knocks, while Tom Trybull and Onel Hernandez are back to full fitness. Grant Hanley (groin) and Christoph Zimmermann (ankle) expect to return following the international break.
Watford welcome Troy Deeney (knee) back to the squad for the first time since August.
Head coach Quique Sanchez Flores also says fit-again Jose Holebas, Etienne Capoue, Sebastian Prodl and Ismaila Sarr are options ahead of the Carrow Road match.
Did you know?
Norwich have won three of their last four league meetings with Watford (L1), with this the first such encounter since a 4-2 Premier League victory in May 2016.
This will be just Norwich’s third Premier League match on a Friday. They lost the first two 5-1 to Tottenham Hotspur in April 1993 and 4-1 to Liverpool on the opening day of this season.
Watford are hoping to avoid becoming the sixth team in history to fail to win any of their first 12 matches of a Premier League season.
All six of Watford's goals this season have come from different players, making them the only Premier League side to have no one score more than once.
Match officials
Referee: Andre Marriner. Assistants: Scott Ledger, Simon Long. Fourth official: Keith Stroud. VAR: Andy Madley. Assistant VAR: Andy Halliday.