Ahead of the 2019/20 season, we look at the new things to keep an eye out for in the Premier League.
The promoted Blades last appeared in the top flight in 2006/07, nine seasons before the Cherries made their debut in the competition.
Having won the Championship title in 2014/15, AFC Bournemouth have been a Premier League club for the last four seasons.
But Eddie Howe's side face a tricky test first up, hosting the team with the best opening-weekend points-per-match average in Premier League history, after two wins and a draw.
It will be a special occasion for David Brooks, who is set to face his former club after joining AFC Bournemouth from Sheff Utd last summer.
The 21-year-old spent three seasons with the Blades and played 30 times for them in the Championship in his final season before moving to the south coast.
The Wales international's Cherries team-mate Simon Francis also played for Sheffield Utd and will hope to return from a knee injury in time to face his former club.
The reverse fixture comes in Matchweek 26, on the weekend of 8 February, at Bramall Lane.
AFC Bournemouth v Sheffield United (10 Aug, 8 Feb)
Sheffield United v Leicester (24 Aug, 2 May)
Burnley v Norwich (21 Sep, 9 May)
Aston Villa v Brighton (19 Oct, 18 Jan)
Brighton v Norwich (2 Nov, 11 Apr)
Sheffield United v Burnley (2 Nov, 11 Apr)
Wolves v Sheffield United (30 Nov, 18 Apr)
Brighton v Sheffield United (21 Dec, 22 Feb)