And history suggests he has the ability to break them.
Although the 31-year-old did not score in Man City's opening match of last season, a 2-0 win at Arsenal, he does love a fast start.
The striker scored twice on his very first Premier League appearance, as a substitute, in a Matchweek 1 victory over Swansea City in August 2011.
But Aguero might hope for even more than two goals in the opening match of Man City's title defence.
After all, Pep Guardiola's side won 4-0 when they last visited London Stadium in November 2018.
And Aguero claimed the winner when the Citizens last met West Ham in the Premier League, at the Etihad Stadium in February.
Last month's meeting at the Premier League Asia Trophy in China was also encouraging for City as they beat the Hammers 4-1.
If Aguero scores three times he will set a second record, surpassing the 11 hat-tricks by the Premier League's all-time leading goalscorer, Shearer, for the most in the competition's history.
But scoring a hat-trick in Matchweek 1 has proved an elusive achievement across the Premier League.
Only seven players in PL history have done so, and none since Didier Drogba in 2010.