The Tottenham Hotspur forward has missed the last four Gameweeks.
But manager Mauricio Pochettino has confirmed that Kane will be assessed after he returned to full training this week.
Owned by just 12.8 per cent of managers, Kane will be a major captaincy contender if he is named on the teamsheet against Burnley for Saturday lunchtime.
He scored a hat-trick in his previous trip to Turf Moor, a 3-0 win in Gameweek 19 last season.
Kane’s recent absence has boosted the appeal of his Spurs team-mate Son Heung-min (£9.0m).
The South Korean is the most-bought player in the Gameweek, earning over 300,000 new owners.
Son will also be among the armband favourites in Gameweek 27, having scored in each of his last three Premier League matches.
And away from home, he has a combined 48 points in his last three outings.