Find out the PL record Sergio Aguero is hoping to extend against Newcastle United and must-know facts for all 10 matches
Arsenal v Cardiff CityArsenal are unbeaten in their last 23 home Premier League fixtures against promoted sides since a 0-1 loss to Newcastle United in November 2010
Fulham v Brighton & Hove AlbionNo side have dropped more points from winning positions in the Premier League this season than Fulham, on 15 occasions, level with Southampton
Huddersfield Town v EvertonHuddersfield Town are looking for their first midweek Premier League victory at the ninth attempt
Wolves v West HamFelipe Anderson has been directly involved in four of West Ham's last five PL away goals, scoring three and assisting another
Manchester United v BurnleySean Dyche is looking to extend his unbeaten record in Premier League matches on Tuesdays, winning three and drawing two.
Newcastle United v Manchester CityMan City striker Sergio Aguero has scored 14 goals in his 12 PL appearances against Newcastle – more than any player has scored against an opponent for a single club in the competition's history
AFC Bournemouth v ChelseaTen of Olivier Giroud’s last 13 PL goals have been as a substitute
Southampton v Crystal PalaceAll three of Wilfried Zaha's PL goals have been scored away from home
Liverpool v Leicester CityOnly Andrew Cole, with 11, and Thierry Henry, with eight, have scored more Premier League goals against Liverpool than Jamie Vardy, with seven
Tottenham Hotspur v WatfordSpurs have scored more headed goals than any other Premier League side this season, with 12