Will Liverpool make it six on the spin? Can Maurizio Sarri's Chelsea follow suit? Find out the best facts from each fixture
Fulham v WatfordNo side has scored more second-half PL goals than Watford this season, with Chelsea matching the Hornets' eight. Only West Ham, with seven, have conceded more than Fulham's six after the interval
Burnley v AFC BournemouthAFC Bournemouth's haul of 10 points from their first five fixtures is their best start to a league season since the 2009/10 League Two campaign, when they had 12
Cardiff City v Manchester CityThis will be the third PL meeting between Cardiff and Man City, with the previous two providing 11 goals; Cardiff winning 3-2 at home and losing 4-2 at the Etihad in 2013/14
Newcastle v Crystal PalaceCrystal Palace have won only one of their last 10 PL matches against Newcastle United
Leicester City v Huddersfield TownJamie Vardy has found the net in his last two league appearances against the Terriers
Liverpool v SouthamptonLiverpool are looking to start a top-flight campaign with six consecutive wins for the third time in their history, after 1978/79, when they finished first, and 1990/91, when they came second
Man Utd v WolvesWolves have won their last two PL matches, both by a 1-0 scoreline. They have not won three in a row in the top flight since March 1980
Brighton v SpursSeagulls striker Glenn Murray has scored four goals in his five PL matches this season, including three in two at the Amex Stadium
West Ham v ChelseaChelsea's Maurizio Sarri could become only the third head coach or manager to win his first six PL matches in charge, after Carlo Ancelotti and Pep Guardiola
Arsenal v EvertonArsenal are unbeaten in 24 home matches against Everton in all competitions (W20 D4) since a 2-1 PL defeat in January 1996 under Bruce Rioch
