Southampton striker Manolo Gabbiadini (groin) is expected to miss out and Sofiane Boufal (knock) will be assessed.
Crystal Palace defenders Scott Dann (knee) and James Tomkins (calf) have been ruled out and left-back Patrick van Aanholt is still unavailable.
Forward Loic Remy is back training and in the squad, Sam Allardyce has confirmed.
Did you know?
Southampton have lost only one of their last 13 home league meetings with Crystal Palace (W9 D3), winning the last five in a row.
Having won the reverse fixture 3-0, Crystal Palace could achieve a first Premier League double over Saints.
Sam Allardyce has never lost a Premier League match at St Mary’s Stadium (W2 D6).
The Eagles have won their last four Premier League matches; they have only won five in a row in the competition on two other occasions (April 2014 and December 1992).
What the managers say
Claude Puel: "It’s important now to find a good balance, to find a clinical edge because we haven’t scored in the last game."
Sam Allardyce: "You'd hope we could target a point, given the form we're in. We have to be 100%. Every player was at their top level Saturday."