Portsmouth celebrated their first ever European match with a 2-0 win over Portuguese side Guimaraes at Fratton Park where both sides missed a penalty.

Aston Villa and Manchester City both came from behind to win 3-1 away at nine-man Litex Lovech of Bulgaria and 2-1 at Omonia Nicosia from Cyprus respectively.

Tottenham Hotspur won for the first time this season beating Polish side Wisla Krakow 2-1 at White Hart Lane.

Lassana Diarra put the home side in front on 39 minutes after breaking in from the left flank and playing a one-two with Jermain Defoe before hitting a first-time finish past keeper Correa Nilson.

Guimaraes could have been level two minutes later after winning a penalty from a Sol Campbell arm over Felix Roberto, but Joao Fajardo's spot-kick effort hit the bar and went over.

In the second period, Defoe won a penalty but had his kick saved by Nilson before he got the crucial second goal, slotting home a great cross from Nadir Belhadj on 60 minutes.

Manchester City came from behind to secure a 2-1 win over Omonia Nicosia in their UEFA Cup opener.

Omonia had gone in front through Klodian Duro, but a brace from Jo ensured City will take a crucial lead into the second leg of the first round contest.

Jo and Stephen Ireland both hit the woodwork before the hosts took the lead four minutes after the break when Duro powered a free-kick into the top corner.

Jo then bundled home a Shaun Wright-Phillips cross 10 minutes later and then nicked the winner on 72 minutes when he fired a neat left-foot effort into the bottom corner.

Gareth Barry scored on his 400th club appearance as Aston Villa came from behind to defeat ill-disciplined Litex Lovech in their UEFA Cup first round first leg clash in Bulgaria.

England midfielder Barry converted a 72nd-minute penalty to celebrate the landmark after the Bulgarian Cup holders were reduced to nine men at the Gradski Stadion.

Nigel Reo-Coker netted for the second time in as many matches to haul Martin O'Neill's side level on the stroke of half-time after a gaffe from goalkeeper Uros Golubovic.

Arguably that mistake altered the shape of the contest and red cards for Cedric Cambon and Mihail Venkov in the second period further enhanced Villa's position in the tie.

Litex's Brazilian-influenced midfield dictated the opening period, however, and they might have added to Bulgaria international Ivelin Popov's curling free-kick which opened the scoring in the 10th minute.

But Villa took further advantage of their numerical advantage when a flowing move put Stiliyan Petrov in on goal in injury time and although Golubovic saved his first attempt, he rolled in at the second attempt.

Everton were rocked at home to Standard Liege when Mbokani was left free to tuck home a low cross on nine minutes but Yakubu Ayegbeni deftly steered home Leon Osman's through-ball 14 minutes later.

However on 35 minutes Joseph Yobo turned the ball into his own net as the Belgian side carved open the defence with almost a carbon copy of their opener.

But again the Merseysiders responded strongly and Segundo Castillo pulled them level three minutes later with a thumping 25-yard volley. David Moyes' men pressed hard but could not find the goal to put them in front for the return leg in Belgium.

Spurs took the lead for the first time this season when David Bentley curled home a left-foot shot on 33 minutes against Polish side Wisla Krakow at White Hart Lane. However the advantage lasted just 67 seconds before Pawel Brozek lifted the ball over Heurelho Gomes from close range.

Darren Bent though headed Tottenham back in front from a Fraizer Campbell cross 17 minutes from time and they held on to take a slender advantage into the away leg.