Chelsea moved level on points with fourth-placed Manchester City in Group 2 after winning 3-2 at Platt lane.
The visitors started the brighter of the two sides and took the lead after just eight minutes through Patrick Bamford's well-worked goal.
Though Jose Pozo La Rosa came close to levelling for Attilio Lombardo’s charges, the impressive Islam Feruz made it 2-0 to the Blues just before the half-hour mark.
Man City halved the deficit thanks to Marco Lopes and the Portuguese 17-year-old almost doubled his tally moments later when he sent a close-range effort just over the bar, but the writing was on the wall when the west Londoners scored again as Bamford's cross was deflected into the City net with 15 minutes remaining.
Lopes did eventually score again with a deflected shot of his own but Chelsea held on to claim their second win of the campaign.
Manchester City match report
Everton 2-1 West Bromwich Albion
Goals in either half by Matthew Kennedy and Hallam Hope earned Everton a narrow win against West Bromwich Albion.
Alan Stubbs' side went into the contest on the back of two straight defeats but a strong side including Victor Anichebe, Thomas Hitzlsperger, Magaye Gueye, Apostollos Velios and Jan Mucha turned in a battling performance to record their fourth victory of the campaign.
Kennedy, who turned 18 years old last week, put the hosts in front with a dazzling run and shot into Luke Daniels’s top corner but, following an injury that forced the withdrawal of Anichebe on 21 minutes, the Baggies, levelled through summer signing Yassine El Ghanassy, who received a pass from Jerome Thomas before firing high past Mucha.
Everton created a number of chances but with the match seemingly destined for a draw substitute Hope jinked into the area and pounced on a loose ball with six minutes remaining.
The win takes the Toffees up to fifth place in Group 1, a point above West Brom.
Everton match report.
Tottenham hit Newcastle for six
Tottenham Hotspur replaced Newcastle United at the top of Group 2 after stunning the visitors with a six unreplied goals in north London.
The Londoners were on the wrong end of a 6-4 humbling on the opening day of the campaign but they made amends in kind at Tottenham Hotspur's training ground.
The hosts took the lead through Ryan Mason's 17th-minute penalty after Alex Pritchard was brought down in the area by Alex Kitchen and eight minutes later it was 2-0 as Christian Ceballos latched on to Andros Townsend's through-ball to beat Jak Alnwick.
Dean Parrett’s header deflected in off Lubo Satka five minutes after the interval and Pritchard made it 4-0 with a fine free-kick, before setting up Jon Obika for the fifth. Obika, a former Crystal Palace loanee, then doubled his tally with two minutes remaining to take Spurs a point above the Magpies after eight matches.
Newcastle match report
Reading end West Ham's run
West Ham United suffered only their second defeat of the Barclays Under-21 season when they went down 3-0 to Reading at Hogwood Park.
The Group 1 leaders had been on a five-match winning run, but goals from Alex Pearce, Jordan Obita and Adam Le Fondre sent Reading to third with 15 points after 10 matches.
West Ham coach Ian Hendon handed goalkeeper Jake Larkins and Frazer Shaw their second starts of the season, while second-year scholar Elliot Lee led the line up front. For Reading Ian Harte, Adam Le Fondre and Pearce were chosen from the first team by Chris Cummins.
Pearce gave Reading the lead after 11 minutes from a Harte corner. The lead was doubled on 56 minutes when Obita scored at the second attempt and after further Reading pressure Le Fondre sealed the win in the final minute, heading in Harte’s cross.
West Ham remain top of Group 1, but next travel to second-place Arsenal on Friday 9 November. Reading next host Bolton Wanderers.
Reading match report | West Ham report
Norwich on the rise
Norwich City moved into third place behind West Ham and Arsenal after beating Blackburn Rovers 3-2 at Ewood Park on Friday night. The visiting team raced into a 3-0 lead after an hour thanks to goals from Reece Hall-Johnson either side of one fom Jamar Loza.
Loza’s goal came after he had claimed the ball in a challenge with Blackburn goalkeeper Grzegorz Sandomierski, who had to leave the field on a stretcher as a result.
Rivers fought back with two goals in the final 30 minutes. John O'Sullivan volleyed home the first before Tim Payne added a second on 74 minutes, but despite their best efforts an equaliser could not be found.
Norwich have 16 points from 10 matches, a point more than Reading, who have played the same number of times.
Blackburn report | Norwich report
Thursday 1 November result
GROUP 2
Sunderland 2-0 Aston Villa
Friday 2 November fixtures
GROUP 1
Blackburn Rovers 2-3 Norwich City
Reading 3-0 West Ham United
Saturday 3 November result
GROUP 2
Tottenham Hotspur 6-0 Newcastle United
Sunday 4 November results
GROUP 1
Everton 2-1 West Bromwich Albion
GROUP 3
Manchester City 2-3 Chelsea
Monday 5 November fixtures
GROUP 1
Bolton Wanderers v Arsenal, Lancashire FA, 7pm
GROUP 2
Manchester United v Stoke City, Altrincham FC, 7pm
Sunderland v Southampton, tbc, 7pm
GROUP 3
Crystal Palace v Middlesbrough, Crawley Town FC, 7pm
Wolverhampton Wanderers v Liverpool, Molineux Stadium, 7pm
For all the fixtures and the latest league tables, click here
You can follow developments on Twitter with the Premier League's account @premierleague or via the hashtag #BU21PL
