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Fabio Borini was Sunderland's hero as his late goal secured a 2-1 win over rivals Newcastle United, the club's first Barclays Premier League victory of the season.
The Italian was introduced in the 68th minute and grabbed the winner with a powerful 85th-minute strike from the edge of the penalty area.
Steven Fletcher gave Gus Poyet the perfect start to his opening game in charge at the Stadium of Light by breaking the deadlock in the fifth minute, but Sunderland were unable to hold on to that lead.
Mathieu Debuchy's first goal for Newcastle brought the visitors level just before the hour, the defender converting a simple tap in at the back post.
Substitute Shola Ameobi came close to winning the game for Newcastle, but it was Borini who ultimately secured three points for the hosts.
The win sees Sunderland move off the bottom of the Premier League table at the expense of Crystal Palace.
Poyet made four changes to the side beaten by Swansea. Andrea Dossena and Carlos Cuellar came into the defence, Jack Colback was selected in central midfield and striker Jozy Altidore replaced joint top-scorer Emanuele Giaccherini.
Youth product Paul Dummett replaced the suspended Mapou Yanga-Mbiwa in the heart of the visitors’ backline, with Fabricio Coloccini and Steven Taylor still absent through injury.
The hosts made a great start as Fletcher headed home his second goal of the season in the fifth minute. Adam Johnson and Sebastian Larsson worked a short corner routine and, when the former stood a ball up to the back post, Fletcher rose above Dummett and beat Krul from close range.
Newcastle failed to pose any real threat in the opening period and were reliant on long shots from Yohan Cabaye as their only moments of promise. The Frenchman fired his first effort over the crossbar and his second, a free-kick, was easily held by Keiren Westwood.
Sunderland almost created a second goal midway through the half, but Fletcher saw his effort palmed away by Krul.
The introduction of Papiss Cisse at the break gave Newcastle more of an attacking threat and 13 minutes into the second half they were level through Debuchy.
Cisse’s introduction released Hatem Ben Arfa and the Frenchman created the equaliser for his compatriot. Ben Arfa’s low cross appeared to evade everyone inside the penalty area but Debuchy ghosted past Johnson to tap home at the back post.
Yohan Cabaye went close to putting the visitors ahead just after the hour, but he saw his curling effort fly just wide of Westwood’s post.
Poyet's decision to introduce Borini nearly paid immediate dividends. The Italian found space on the left of the penalty area and saw his low shot slip through the legs of Krul, only for the goalkeeper to react quickly and pounce on the ball.
However, Borini was not to be denied and, after Ameobi had drilled an effort wide from 20 yards, he rounded off a flowing move to register his first goal for the club.
Sunderland head coach Gus Poyet: "When you're bottom it's not nice. We're off - that is something. We beat our biggest rivals, that’s even bigger. Now we need to keep going; we need to start passing the ball better; we need to keep believing. This is what we needed, so from now on there are no excuses. We needed a lift, and there is no better lift than this one.
"[The substitutes] were outstanding. If we didn’t control a little of the ball I felt we would have been defending for 20 minutes and I didn’t want to defend for 20 minutes. Even if it was a little bit slower, we needed to do it [make the change]. We gave so much that it was impossible to retain that energy.
"Fabio was so close to playing. The way he's been training, his attitude, how positive he is, but sometimes you cannot play him."
Newcastle United manager Alan Pardew: "I feel disappointed for our fans and the team; they didn’t deserve that. I thought they deserved to win. They just switched off. A little bit of professionalism cost us.
"After the start I thought we settled down reasonably well. We changed our system a little bit. It started to pay dividends from 20 minutes in and right up until their second goal I was really pleased."
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