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Two goals by Moussa Sissoko helped Newcastle United secure their biggest Barclays Premier League win of the season and their first league success against Hull City since 1990.
Loic Remy and Vurnon Anita were also on target for the Magpies, who conceded a goal to Hull defender Curtis Davies before witnessing the dismissal of their manager Alan Pardew after he became involved in a clash of heads with Tigers' midfielder David Meyler.
Sissoko converted Mathieu Debuchy's cross to give Newcastle the lead, which was doubled by in-form Remy in the closing stages of the first half. Hull pulled a goal back through Davies, only for Sissoko and Anita to make sure of the points.
Mapou Yanga-Mbiwa was named in the Newcastle defence in the absence of captain Fabricio Coloccini, and it was the visitors who made the better start to proceedings with Yoan Gouffran firing narrowly wide early on from the edge of the area.
However Hull would have taken the lead after nine minutes if Magpies goalkeeper Tim Krul had not produced a fine double save to deny Alex Bruce's header and Shane Long's close-range follow-up.
The Dutchman's heroics were rewarded less than 30 seconds later when Sissoko turned Debuchy's low right-wing cross into the top corner with an emphatic finish for his first goal since November.
The hosts almost responded immediately as Long headed just over the bar from Liam Rosenior's delivery and Nikica Jelavic wasted a similar opportunity.
Hull continued to create the better chances but were denied by the woodwork after 35 minutes when Jelavic's curling free-kick was deflected against the bar before Ahmed Elmohamady nodded Long's magnificent cross wide of the mark.
And Hull were made to pay for their profligacy three minutes prior to the interval as Remy capitalised on a misplaced backpass from Maynor Figueroa by rounding goalkeeper Allan McGregor and slotting into the empty net.
Steve Bruce's side were quick out of the blocks in the second half and instantly pulled one back following the restart as Davies headed home Tom Huddlestone's inswinging free-kick.
But Newcastle restored their two-goal advantage in the 55th minute when Sissoko tapped home a rebound from Yoan Gouffran's shot as he finished off a counter-attack that he had started.
Pardew was given his marching orders in the 72nd-minute after becoming involved in an argument on the touchline as Meyler came to retrieve the ball, making contact with the midfielder with his head, but the Magpies remained unaffected and continued to push on for a fourth with Luuk de Jong going close to his first goal for the club before Remy was brilliantly denied by a flying save from McGregor.
The visitors did score again at the death when Anita tapped in with almost the final kick following good work from Dan Gosling and Paul Dummett.
Hull manager Steve Bruce: "We played fantastically well first half, we've had a great chance, then a bit of quality from Newcastle and we're 1-0 down
"Then we've had Jelavic's chance, Elmohamady's chance, Jelavic hits the bar and then we go and make a mistake like you see on a Sunday morning park pitch, and you can't do that at this level. We've made more mistakes today than I remember us making in six months and when you play at this level you can't do that.
"Collectively and individually, we've made just basic, bad schoolboy errors, we've basically give them three goals in my opinion and when you do that it's always going to be a difficult afternoon and we rightly got punished."
"In football, tensions run high, the pressure on Premier League managers is enormous, unfortunately he's lost his head which is not like Alan. I'm sure Alan's absolutely regretting it and questioning himself, asking 'how the hell have I done that?'. It's not like Alan, he's an established Premier League manager.
"I'm delighted with the reaction of David Meyler because other people would've been rolling round the floor. We've all done silly things in the heat of the moment."
Newcastle manager Alan Pardew: "I tried to push him (Meyler) away with my head and I shouldn't have done that. My team were terrific and it's only myself who had a poor performance. Of course I apologise. I represent a big club.
"It was a heat of the moment thing. I massively regret it and I will have to sit down from now on. It's a shame because it took the gloss off a fantastic performance from us. That's really upsetting."
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